Yijing Wu1, Kevin M. Johnson1, Elizabeth J. Nett1, Patrick Turski2, Charles A. Mistretta3
1Medical Physics, University of Wisconsin, Madison, MADISON, WI, USA; 2Radiology, University of Wisconsin, Madison, MADISON, WI, USA; 3Medical Physics and Radiology, University of Wisconsin, Madison, MADISON, WI, USA
Phase Contrast (PC) HYPR FLOW, which employs post contrast PC VIPR images as the composite and reconstructs the first pass time resolved contrast enhanced VIPR acquisition using HYPR LR technique, is able to achieve 4D Contrast Enhanced (CE) MRA with both high temporal resolution and isotropic spatial resolution and quantitative flow dynamics from the PC images. PC HYPR FLOW was performed on normal subjects and patients with brain AVMs. 4D CE MRA images with sub-second temporal resolution and sub-millimeter isotropic spatial resolution were generated as well as the flow dynamic maps including the wall shear stress and pressure. Quantitative measurements of velocity, WSS and pressure gradients were conducted and compared between control and patient groups.