Jerry S. Cheung1,2, Shu Juan Fan1,2, April M. Chow1,2, Edward S. Hui1,2, Ke Xia Cai1,2, Kwan Man3, Ed X. Wu1,2
1Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China; 2Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China; 3Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Hepatic ischemia/reperfusion injury (IRI) occurs during liver transplantation, tumor resection, hemorrhagic shock and veno-occlusive disease, and is a major cause of acute liver failure. IRI in liver is also responsible for early organ failure and increased incidence of both acute and chronic rejection after liver transplantation. This study aims to examine the changes of diffusion measurements by diffusion tensor imaging (DTI). The experimental results demonstrated that DTI is useful in identifying hepatic IRI by characterizing the transient changes in mean diffusivity and fractional anisotropy.