Kristina Ringe1, R Gupta2, Angela Reichel1, Thomas Rodt1, Sabine Dettmer1, Nils Hellige3, Michael Galanski4, Elmar M. Merkle2, Joachim Lotz5
1Department of Radiology, Hannover Medical School, Hannover, Germany; 2Department of Radiology, Duke University School of Medicine, Durham, NC, USA; 3department of Radiology, Hannover Medical School, hannover, Germany; 4Department of Radiology, Hannover Medical School, hannover, Germany; 5Department of Radiology, Hannover Medical School, Hannover , Germany
T2-weighted respiration navigated MRCP was performed before and 3.3+/-0.4min after administration of GD-EOB-DTPA in 21 patients. SNR in bile ducts was assessed to quantify alterations in the quality of MRCP induced by biliary excretion of the contrast agent. SNR decreased by 26.5 +/- 33.5% in the MRCP after the injection of GD-EOB. Maximal decrease of SNR was 90% making the MRCP non-diagnostic. A non-significant tendency for larger decreases of SNR in younger patients and preserved SNR in patients with parenchymal disease was seen. GD-EOB-DTPA should be injected after a T2w-MRCP to avoid negative effects on the quality of the MRCP.