Wei Bian1, Jason C. Crane1, Wonjoon Sohn2, Ilwoo Park1,3, Esin Ozturk-Isik1, Sarah J. Nelson1,3
1Radiology, University of California San Francisco, San Francisco, CA, USA; 2Computer Science, University of California Berkeley, Berkeley, CA, USA; 3Program in Bioengineering, University of California San Francisco, San Francisco, CA, USA
Two phase correction strategies for the reconstruction of multi-channel MRSI were compared in this study. The first is to find the optimal phase for voxels from each channel prior to coil combination. The second is to determine the optimal phase from the sum of the spectra from the central 8 voxels from each channel, and then applying this phase to all voxels in that channel prior to coil combination. Results from phantom and glioma patient experiments showed that the first strategy yielded a slightly improved phase correction for high SNR data but the second was more robust and accurate for the clinical relevant flyback echo-planar encoding data.