Wanyong Shin1, Geng Xiujuan1, Hong Gu1, Yihong Yang1
1Neuroimaging Research Branch, National Institute on Drug Abuse, Baltimore, MD, USA
In this study, an automated brain tissue segmentation method based on modeling of individual quantitative T1 values of brain tissues is proposed. To accomplish it, a fast T1 mapping using inversion recovery Look-Locker echo-planar imaging at a steady state (IR LL-EPI SS) with whole brain coverage is presented. This method is insensitive to instrumental settings and can be used to address specific patient populations and age-dependent groups.