Ludovic de Rochefort1,2, Tian Liu1, Bryan Kressler1, Jian Liu1, Pascal Spincemaille1, Jianlin Wu3, Yi Wang1
1Radiology, Weill Medical College of Cornell University, New York, NY, USA; 2LMN, MIRCen, I2BM, DSV, CEA, Fontenay-aux-roses, France; 3Radiology, The 1st Hospital of Dalian Medical University, Dalian, Liaoning Province, China
A reconstruction technique is presented to extract susceptibility maps from phase and magnitude MR data. The linear problem is solved using least-square regularization based on two terms to define boundary conditions and preserve edges. The technique is validated on phantom and applied in human to quantify iron in cerebral hemorrhage.