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Abstract #0478

Cardiac Magnetic Resonance (CMR) Evaluation of Patients with ST-Elevated Acute Myocardial Infarction (STEMI): Influence of Time-To-Reperfusion on the Extent of the Area at Risk, Infarct Size and Microvascular Damage

Iacopo Carbone1, Marco Francone2, Emanuela Algeri2, Ilaria Iacucci2, David Cannata2, Luciano Agati2, Carlo Catalano2, Roberto Passariello2

1La Sapienza University of Rome, Rome, Italy, Italy; 2La Sapienza University of Rome, Italy


Seventy STEMI patients treated with primary PCI within 12 hours from symptom onset underwent CMR in the first week after hospital admission to assess the influence of time to reperfusion on infarct size, microvascular damage and salvaged myocardium. A progressive increase of infarct size and microvascular damage over time has been observed. However, the new finding of the present study is that salvaged myocardium suddenly decreases after 60 minutes of coronary occlusion confirming the importance to shorten the delay in STEMI treatment.