Ting Song1, Maureen N. Hood2, Vincent B. Ho3, Sandeep N. Gupta4, Jeffrey A. Stainsby5
1Applied Science Laboratory, GE Healthcare, Bethesda, MD, USA; 2Radiology, Uniformed Services University of the Health Sciences and National Naval Medical Center, Bethesda, MD, USA; 3Radiology, Uniformed Services University of the Health Sciences and National Naval Medical Center, Bethesda, Bethesda, MD; 4GE Global Research, Niskayuna, NY, USA; 5Applied Science Laboratory, GE Healthcare, Toronto, ON, Canada
Cardiac T1 mapping provides a quantitative way to characterize tissue abnormalities, such as myocardial infarction and amyloidosis. IR prepared SSFP, CINE-IR, and the modified look-locker saturation-recovery (MLLSR) were evaluated on both phantoms and human studies in this paper. The sensitivity of these techniques to variations in heart rate and flip angle were compared. The MLLSR sequence gave consistent, reliable results across the widest range of T1 values, flip angles and heart rates.