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Abstract #0485

Navigator-Gated T2 and T2*-Weighted Imaging of Myocardial Edema and Hemorrhage Following Primary Coronary Intervention

Declan Patrick O'Regan1, Rizwan Ahmed2, Giuliana Durighel1, Amy McGuinness1, Jo V. Hajnal1, Stuart A. Cook2

1Robert Steiner MRI Unit, Imaging Sciences Department, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, UK; 2Molecular Cardiology Group, MRC Clinical Sciences Centre, Hammersmith Hospital, Imperial College London, London, UK


We assessed the feasibility of using T2* mapping to quantify regions of myocardial hemorrhage following percutaneous primary coronary intervention (PPCI) for acute myocardial infarction. We also assessed myocardial edema imaging using a T2-weighted asymmetric turbo spin echo with spectrally-selective inversion recovery (SPIR) fat suppression. To reduce respiratory motion artifact and ghosting from the blood pool we used navigator gating and a black blood prepulse in both sequences. Our findings show that hemorrhage is frequently observed following PPCI and is an indicator of poor myocardial salvage.