Vishal Patil1, Glyn Johnson1, Jens H. Jensen1
1Radiology, NYU School of Medicine, New York, USA
Estimation of gadolinium concentration, [Gd], is the essential first step in the measurement of a number of different parameters by contrast enhanced perfusion MRI. Generally, [Gd] is estimated assuming a linear relationship between relaxation rate and concentration. However, it is known that this assumption is false in tissue. Magnetic Field Correlation (MFC) depends quadratically on [Gd] to a very good approximation and may therefore be a more accurate means of estimating concentration. The purpose of this study is to compare the accuracy of [Gd] measurement using MFC and relaxivity rates in yeast phantoms.