XIANG LIU1, WEI TIAN2, Sven Ekholm1
1Department of Radiology, University of Rochester Medical Center, Rochester, NY, USA; 2Department of Radiology, ; University of Rochester Medical Center, Rochester, NY, USA
The purpose of this study is to evaluate the value of DTI in differentiating tumefactive demyelinating lesions (TDL) with high grade gliomas, which is important to avoid unnecessary surgical procedures, but difficult on conventional MR images alone. The mean FA values of TDLs were significantly higher than those of high grade gliomas, without difference of ADC between groups. And fiber density index in the high grade gliomas was significantly reduced compared with TDLs, accompanied with significant change of main eignvector in the peri-tumoral region. DTI are useful and assist in differentiating between the TDLs and high grade gliomas.