Ulrika E. Svanholm1, Magnus Mrtensson1, Brigitte Vollmer2, Linda Holmstrm3, Atsushi Takahashi4, Bo Nordell1, Olof Flodmark5
1Department of Hospital Physics, Karolinska University Hospital, Stockholm, Sweden; 2Department of Woman nad Child Health, Karolinska Institute, Neuropediatric Research Unit, Stockholm, Sweden; 3Department of Woman and Child Health, Karolinska Institute, Neuropediatric Research Unit, Stockholm, Sweden; 4Global Applied Science Laboratory, GE Healthcare Technologies, Menlo Park, CA, USA; 5Department of Nuroradiology, Karolinska University Hospital, Stockholm, Sweden
Using MRI with ultra-short echo time (UTE), it has been shown that white matter contains both long and short T2 components, and that the latter can be connected to myelin. In this work it was investigated whether patients with white matter injury of immaturity could benefit from imaging with UTE. The results show that UTE images can be useful in detecting white matter abnormalities; the contrast utilized in UTE images is different from both that of T2 and diffusion weighted images, indicating that UTE could be a valuable complement to these techniques in imaging atypical white matter.