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Abstract #1191

White Matter Damage in End-Stage Renal Disease: Assessment with Diffusion-Tensor Imaging

Tsyh-Jyi Hsieh1,2, Twei-Shiun Jaw2,3, Jer-Ming Chang4,5, Hung-Yi Chuang6,7, Chih-Hung Ko8,9

1Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Taiwan; 2Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Taiwan; 3Faculty of Medical Radiation Technology, College of Health Sciences, Kaohsiung Medical University, Taiwan; 4Department of Internal Medicine, Hsiao-Kang Municipal Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Taiwan; 5Department of Nephrology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Taiwan; 6Faculty of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan, Taiwan; 7Department of Environmental and Occupational Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Taiwan; 8Department of Psychiatry, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Taiwan; 9Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Taiwan


In patients with end-stage renal disease (ESRD), the causes of neurologic complications are complex and a non-invasive, subjective method to predict the occurrence of these complications is needed. The aim of our study was to prospectively determine regional differences of anisotropy between ESRD patients and normal controls and the effect of dialysis on microstructure changes of the white matter.