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Abstract #1196

Simultaneous EEG-CBV (Electroencephalography Cerebral Blood Volume) Measurements of Epileptic Spikes

Michiro Negishi1, Maolin Qiu1, Robert Todd Constable1,2

1Diagnostic Radiology, School of Medicine, Yale University, New Haven, CT, USA; 2Neurosurgery, School of Medicine, Yale University, New Haven, CT, USA


Simultaneous EEG and VASO (Vascular Space Occupancy) imaging can be used to characterize CBV (cerebral blood volume) changes during interictal epileptic discharges (IEDs). However, the VASO sequence causes more RF pulse artifacts in the EEG than spin-echo or gradient-echo functional MRI (fMRI) sequences. In this research, we compared the RF artifacts generated by different types of wiring in the EEG system, and found that the RF pulse can be eliminated with a proper connection method. We also showed the feasibility of simultaneous EEG-VASO measurements.