João MN Duarte1, Anita Frank2, Kim Q. Do2, Rolf Gruetter1,3
1Centre d'Imagerie BioMedicale, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland; 2Schizophrenia Research Unit, Center for Psychiatric Neuroscience, Univ. Hosp. Lausanne, Lausanne, Switzerland; 3Departments of Radiology, Universities of Lausanne and Geneva, Switzerland
The in vivo NMR scanning of animals at different stages of development requires recurrent anaesthesia. The present study investigated whether recurrent isoflurane anaesthesia during development has an effect on the cortical neurochemical profile of the adult mice.