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Abstract #1309

Diffusion Tensor Imaging of Subjects with Cervical Spondlytic Myelopathy: Use of the Eigenvalues as Indicators of Spinal Stenosis

Enedino Hernandez1,2, Alex L. Mackay3,4, Erin L. MacMillan5, Burkard Mdler6, David K. Li2, M F. Dvorak7, Teodoro Cordova8, Alonso Ramirez-Manzanares9, C Laule2

1Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajuato, Mexico; 2Dept. of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; 3Dept. of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; 4Dept. of Physics & Astronomy, University of British Columbia, Vancouver, British Columbia, Canada; 5Dept. of Clinical Research, University of Bern, Bern, Switzerland; 6Philips Healthcare, Vancouver, British Columbia, Canada; 7International Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada; 8Fisica Medica y Materiales Biologicos, Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajuato, Mexico; 98Facultad de Matematicas, Universidad de Guanajuato, Guanajuato, Mexico


In this work the results of a study investigating Cervical Spondylotic Myelopathy subjects using DTI are presented. We analyzed the FA as well as the parallel (LP) and radial (LR) eigenvalues of the diffusion tensor in stenotic and normal appearing regions of the cord. Diffusion Tensor eigenvalues were approximately constant along the spine, but with variations in regions with stenosis. FA was generally higher in the stenotic regions; however, LP and LR were generally reduced in regions of stenosis.