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Abstract #1343

Feasibility of Imaging Mesenchymal Stem Cells in Vitro Using Standard MRI Sequences

Emidio Tarulli1, Voytek Gretka2, Amy Hoyles3, Cindi Morshead3, Greg J. Stanisz2

1Department of Medical Biophysics, University of Toronto, Toronto , ON, Canada; 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; 3Department of Surgery, University of Toronto, Toronto, ON, Canada


While stem cell therapies of stroke have shown success in structural and functional recovery of lost tissue, the ability to track cell migration and distribution in a non-invasive manner remains a work in progress. This study demonstrates the ability to track single rat mesenchymal stromal cells (rMSCs) labeled with micron-sized superparamagnetic iron-oxide (MPIO) particles (Bangs Labs, MC05F) with standard MRI sequences in vitro.