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Abstract #1564

White Matter FMRI: Exploring Functional Differentiation in the Corpus Callosum

Jodie R. Gawryluk1,2, Kim Dillen1, Kim D. Brewer1,2, Erin L. Mazerolle1,2, Steven D. Beyea1,2, Ryan CN D'Arcy1,2

1Institute for Biodiagnostics (Atlantic), National Research Council Canada, Halifax, Nova Scotia, Canada; 2Dalhousie University, Halifax, Nova Scotia, Canada


The ability to detect fMRI activation in white matter has been a matter of considerable debate. We have recently reported the first two prospective 4T fMRI studies, which used interhemispheric transfer tasks to elicit activation in the corpus callosum. These studies used different tasks and reported activation in functionally appropriate and separable white matter regions. The current study replicated these activation results using a within subjects design and showed that task type can be used to map functional specialization in white matter.