Jerod Michael Rasmussen1, Sumiko Abe1, Liv C. McMillan1, Josef Pfeuffer2, Jessica Turner1, Function BIRN3
1University of California, Irvine, Irvine, CA, USA; 2Siemens Medical Solutions; 3www.nbirn.net
A comparison of calibration methods and their effect on the strength of correlations between: Cerebral Blood Flow (CBF), a hypercapnic task and a cognitive task. Calibration methods compared are the different permutations between active state CBF, resting state CBF, composite maps of hypercapnic breath holding and composite maps of a cognitive sensorimotor task. Each composite map has a highly temporally correlated interleaved ASL/BOLD and a traditional EPI BOLD acquisition version for comparison. Results demonstrate that using the active CBF ascertained from the interleaved ASL/BOLD acquisition method has the highest potential for calibration.