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Abstract #1672

Deconvolved FMRI Correlates with Source-Localised MEG as a Function of Neural Frequency Oscillation

Johanna M. Zumer1, Claire M. Stevenson1, Matthew J. Brookes1, Sue T. Francis1, Peter G. Morris1

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK


BOLD fMRI is widely used for inferring neural activity from the indirect haemodynamic response that it measures. MEG measures direct neuromagnetic effects across time and frequency and recent techniques enable a full spatial-temporal-frequency reconstruction of neural sources. Here, we deconvolved a BOLD response to a 4s visual stimulus with the haemodynamic response function to get an estimate of neural activity from fMRI. We correlated this prediction with the source-localised result from MEG across frequency bands and found a significant negative correlation with lower frequencies (4-25Hz) and a significant positive correlation with high frequencies (52-98Hz).