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Abstract #1678

Opposite Parietal and Midbrain BOLD Patterns During Inflammatory Pain in the Rat: A High-Field FMRI Study

Ariel Graff-Guerrero1,2, Juan Manuel Ortega-Legaspi3, Camilo De la Fuente-Sandoval4, Francisco Pellicer3, Desiree Lpez5, Alvino Moreno5, Rodrigo Martn5, Sergio Solis5, Silvia Hidalgo5, Alfredo O. Rodriguez5

1Instituto de Neurobiologia, Universidad Nacional Autonoma de Mexico, Mexico, DF, Mexico; 2PET Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada; 3Laboratorio de Neurofisiologa Integrativa, Instituto Nacional de Psiquiatria Ramon de la Fuente, Mexico; 4Laboratorio de Psiquiatria Experimental, Instituto Nacional de Neurologia y Neurocirugia, Mexico; 5Electrical Engineering Department, Universidad, Autnoma Metropolitana-Iztapalapa, Mexico, DF, Mexico


The development of high-field magnetic resonance scanners, for small animals, have redirected the study of pain using fMRI in preclinical models. While human studies have advantages to study cognitive-psychological processes during pain perception, animal studies allow to correlate fMRI with basic mechanisms.