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Abstract #1742

Validation of Cine-FLASH as a Method to Image Late Gd Enhancement in Mice

Andrea Protti1, Alexander Alexander Sirker2, Tobias Schaeffter3, Ajay Shah2, Rene Botnar3

1Cardiovascular Division and Division of Imaging Sciences, Kings College London BHF Centre of Excellence, London, UK, UK; 2Cardiovascular Division, Kings College London BHF Centre of Excellence, London, UK; 3Division of Imaging Sciences, Kings College London BHF Centre of Excellence, London, UK


Late Gadolinium Enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is usually performed by a T1-weighted sequence with an inversion recovery (IR) pre-pulse. Although the images achieve good contrast from areas of Gd agent uptake, there are several drawbacks such as absence of contrast between Gd infarcted areas and blood; image blurring due to ECG and respiration instability; anatomical information lost. In order to avoid such limitations, a cine-FLASH is suggested as a more reliable method of imaging LGE in mice 2 days after MI.