Frank Grothues1, Hagen Boenigk1, Martin Kanowski2, Joachim Graessner3, Katrin Christel Sprung3, Martin Rohrer4, Ruediger Christian Braun-Dullaeus1
1Cardiology, University Hospital Magdeburg, Magdeburg, Germany; 2Neurology, University Hospital, Magdeburg, Germany; 3Siemens Medical Solutions, Erlangen, Germany; 4Bayer Schering Pharma AG, Berlin, Germany
Two doses of gadobutrol (0.1 mmol/kg or 0.2 mmol/kg) were evaluated qualitatively and quantitatively for late enhancement (LE) imaging at 3T in an intra-individual comparison in 15 patients with a history of myocardial infarction. Qualitative judgement by blinded observers revealed an in tendency better image quality with fewer artifacts and less noise with the higher contrast dosage. Quantitative measurements of infarct size and contrast-to-noise ratio between infarcted and remote myocardium were significantly higher with the 0.2 mmol/kg dosage and should therefore be preferred.