Kirsi M. Taimen1, MIchael C. Yang1, Karin Dill1, John Sheehan1, James C. Carr1
1Department of Radiology, Northwestern University, Chicago, IL, USA
Amyloidosis is a systemic disease caused by extracellular deposition of insoluble protein. Cardiac involment is common and often fatal form of disease. Cardiovascular magnetic resonance exhibits late enhancement and shorter T1 in cardiac amyloidosis. We assessed T1 signal in cardiac amyloidosis using T1 weigheted gradient echo (GRE) technique and compared findings in age-matched control group. Results show that left ventricular myocardium is T1 hyperinterse on pre-contrast T1-GRE imaging in patients with suspected amyloidosis. They also have a shorter TI compared to controls following contrast administration.