Stefan Weber1, Gesine Maria Wirth, R Peter Kunz, Michael B. Pitton, E Mayer2, Chistoph Dber, Karl Friedrich Kreitner
1Section of Medical Physics, Department of Radiology, Mainz University Medical School, Mainz, Germany; 2Department of Cardiothoracic and Vascular Surgery, Mainz University Medical School, Mainz, Germany
The aim of this study was to validate the estimation of the mean pulmonary artery pressure (mPAP) using high temporal resolution phase-contrast magnetic resonance flow measurements with invasive catheter-based pressure measurement. Seven patients with chronic thromboembolic pulmonary hypertension (CTEPH) underwent simultanously acquired catheter-based pressure measurement and high temporal resolution phase-contrast MRI. A very high correlation of calculated mPAP values from MRI data derived from flow parameters and invasive measured mPAP was found (R=0.99). Therefore, non-invasive mPAP-estimations are possible in CTEPH-patients by means of high temporal resolution PC-MRI and correlate well with simultaneous invasively measured values.