Jeon-Hor Chen1,2, F-T Hsu2, H-N Shih2, C-C Hsu2, Daniel Chang1, K Nie1, O Nalcioglu1, M-Y Su1
1Center for Functional Onco-Imaging, University of California Irvine, Irvine, CA, USA; 2Department of Radiology, China Medical University Hospital, Taichung, Taiwan
In this study we measured MR-based breast density in patients with IDC and DCIS, also between patients with ER-positive and ER-negative cancer and investigated whether they show significant differences. IDC and DCIS did not showed any significant difference in the breast density, suggesting that density alone might not predict differential risk for patients who will develop IDC vs. DCIS. Breast density between ER-positive and ER-negative patients was also not significantly different, suggesting the link between breast density and breast cancer may be due to factors other than or in addition to estrogen exposure.