Barbara Holshouser1, Gregory Aaen2, Clare Sheridan2, Melinda McKenney3, Udo Oyoyo1, Stephen Ashwal2
1Radiology, Loma Linda University Medical Center, Loma Linda, CA, USA; 2Pediatrics, Loma Linda University Medical Center, Loma Linda, CA, USA; 3School of Medicine, Loma Linda University, Loma Linda, CA, USA
Traumatic brain injury in children under 2 years of age is attributed to non-accidental trauma (NAT) in 24% to 32% of cases. Outcome in victims of NAT is recognized to be worse possibly due to a hypoxic-ischemic component. A retrospective analysis of 109 children with confirmed NAT was performed to measure regional metabolite changes observed with single voxel and multivoxel (MRSI) proton spectroscopy through the level of the corpus callosum to determine if metabolite changes can predict long-term neurologic outcome.