Rikke Beese Dalby1, Jamila Ahdidan1, M. Mallar Chakravarty2,3, Leif Srensen4, Raben Rosenberg1, Leif stergaard2, Poul Videbech1
1Centre for Psychiatric Research, Aarhus
University Hospital, Risskov, Denmark; 2Center of Functionally
Integrative Neuroscience, Aarhus University Hospital, Aarhus, Denmark; 3PET
Center, Aarhus University Hospital, Aarhus, Denmark; 4Department of
Neuroradiology, Aarhus University Hospital, Aarhus, Denmark
Neuroimaging studies in major depression (MD) have revealed an increased frequency of cerebral white matter lesions (WMLs) and abnormalities in regional cerebral blood flow (CBF) in multiple fronto-limbic structures, which may cause cognitive dysfunction. However, the impact of WMLs on the neuronal network and the concurrent role of cerebral perfusion are not yet fully understood.
Human Brain Tumor Imaging