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Abstract #3728

Functional Connectivity Networks Associated with Dorsal and Ventral Striatum

Aman Goyal1, Wendy Ringe2, Kaundinya Gopinath3,4, Robert Haley4, Richard Briggs3

1Graduate Program in Biomedical Engineering, UT Southwestern Medical Center, Dallas, TX, USA; 2Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA; 3Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA; 4Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA


Functional connectivity networks associated with dorsal (DS) and ventral striatum (VS) were studied with BOLD FcMRI. The VS exhibited strong connections with a ventral and medial anterior prefrontal network consistent with its limbic connections. The DS demonstrated strong connections along a more dorsal and lateral prefrontal network. Additionally, the DS demonstrated stronger negative correlation with primary sensory, lateral parietal cortices and superior cuneus than VS. Both the VS and DS exhibited strong connections to the medial dorsal nucleus of the thalamus. Results are highly consistent with previous studies of the anatomical and hypothesized functional connections of these two networks.