Aoife N. Keeling1, Cormac Farrelly1, John Sheehan1, William Pearce2, Timothy J. Carroll3, Mary M. McDermott4, James C. Carr1
1Dept of Cardiovascular Imaging, Northwestern Memorial Hospital, Chicago, IL, USA; 2Department of Vascular Surgery, Northwestern Memorial Hospital, Chicago, IL, USA; 3Dept of Cardiovascular Imaging, Dept of Biomedical Engineering, Northwestern Memorial Hospital, Chicago, IL, USA; 4Department of Preventative Medicine, Northwestern Memorial Hospital, Chicago, IL, USA
Peripheral arterial disease (PAD) severity, as assessed by ankle brachial index (ABI), significantly correlates with the degree of functional impairment. However, a correlation between the severity of PAD, as determined by time resolved magnetic resonance angiography (MRA), and functional limb impairment has not been determined. 58 patients with known PAD had time resolved MRA performed using a TWIST sequence on a 1.5T Siemens Espree MRI scanner, with single dose Magnevist. Time resolved peripheral magnetic resonance angiographic lesion severity and collateral grade significantly correlates with lower limb functional impairment in patients with PAD.