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Abstract #3946

Comparative Analysis of Capability for Bone Metastases Assessment Among Whole-Body Diffusion-Weighted Imaging, Whole-Body MR Imaging Without and with Diffusion-Weighted Imaging, Bone Scan and Whole-Body FDG-PET/CT in Non-Small Cell Lung Cancer Patients

Keiko Matsumoto1, Yoshiharu Ohno1, Hisanobu Koyama1, Munenobu Nogami2, Daisuke Takenaka1, Yumiko Onishi1, Nobukazu Aoyama3, Hideaki Kawamitsu3, Kazuro Sugimura1

1Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; 2Division of Image-Based Medicine, Institute of Biomedical Research and Innovation, Kobe, Hyogo, Japan; 3Division of Radiology, Kobe University Hospital, Kobe, Hyogo, Japan


Accurate tumor staging is essential for choosing the appropriate treatment strategy in non-small cell lung cancer (NSCLC) patients. Recently, whole-body MRI without and with diffusion-weighted image (DWI) has been suggested as useful for assessment of distant metastases in oncology patients. However, no direct comparison of diagnostic accuracy for bone metastasis assessment has been made among whole-body MR imaging without and with DWI, bone scan and FDG-PET/CT in NSCLC patients. The purpose of this study was to prospectively and directly compare the capability for bone metastasis assessment whole-body MR imaging with and without DWI, integrated FDG-PET/CT and bone scan.