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Abstract #3965

Accelerated MR Protocol for Cartilage Volume Analysis and Whole-Organ Joint Assessment for Osteoarthritis Research Studies

Vaishali Soneji Lafita1, Richard Kijowski1, David Rabago2, Michael Woods1, Dana Tudorascu3, Jessica Klaers4, Walter Block4,5

1Radiology, University of Wisconsin, Madison, WI, USA; 2Family Medicine, University of Wisconsin, Madison, WI, USA; 3Statistics, University of Wisconsin, Madison, WI, USA; 4Medical Physics, University of Wisconsin, Madison, WI, USA; 5Biomedical Engineering , University of Wisconsin, Madison, WI, USA


This study was performed to determine whether an 8 minute accelerated MR protocol consisting of isotropic resolution VIPR-SSFP and sagittal fat-suppressed T2-weighted FSE sequences could be used to provide rapid cartilage volume analysis and whole-organ joint assessment for osteoarthritis research studies. Cartilage volume measurements and whole-organ joint assessment using the WORM system were performed on 20 patients enrolled in an osteoarthritis research study using a 20 minute standard MR protocol and the accelerated MR protocol. There was a small mean difference of 0.27cm3 between cartilage volume measurements and strong correlation between WORM scores obtained using the standard and accelerated protocols.