Hersh Chandarana1, Kinh Gian Do1, Ely Felker1, Cristina Hajdu2, Jens Jensen1, Bachir Taouli1
1Radiology, NYU Medical Center, New York, NY, USA; 2Pathology, NYU Medical Center, New York, NY, USA
We assessed the effect of hepatic iron deposition on liver signal intensity and apparent diffusion coefficient on diffusion-weighted images in cirrhotic patients. Our preliminary results show that severe iron deposition significantly lowers liver signal intensity on DWI for b0 and b500, and also decreases apparent diffusion coefficient (ADC) without reaching significance. The effect of hepatic iron deposition should be taken into account when using ADC for the diagnosis of liver fibrosis/cirrhosis.