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Abstract #4090

MR Elastography for the Early Detection of Steatohepatitis in the Rat with Fatty Liver

Najat Salameh1, Benot Larrat2, Jorge Abarca-Quinones1, Stphane Pallu1, Mylne Dorvillius1, Isabelle Leclercq3, Mathias Fink2, Ralph Sinkus2, Bernard E. Van Beers1

1Radiodiagnostic Unit, Universit Catholique de Louvain, Brussels, Belgium; 2Laboratoire Ondes et Acoustique, Ecole Suprieure de Physique et Chimie Industrielles, Paris, France; 3Gastroenterology Unit, Universit Catholique de Louvain, Brussels, Belgium


The early and non-invasive detection of non-alcoholic steatohepatitis in the fatty liver is difficult. The aim of our study in the rat was to assess the potential value of MR elastography for this non-invasive detection. Our results in the rat suggest that in non-alcoholic fatty liver, MR elastography may be useful for the early detection of steatohepatitis by showing increased elasticity appearing before fibrosis development and linked to myofibroblast activation.