Lutz Ldemann1, Tobias Franiel2, Matthias Taupitz2, Hagen Rehbein1, Dirk Beyersdorff2
1Department of Radiotherapy, CVK, Charit, Berlin, Germany; 2Department of Radiology, Charit, Berlin, Germany
Contrast enhancement of the prostate in dynamic MR imaging can be used to assess perfusion and permeability using a low-molecular-weight con-trast medium. The arterial input function is subject to delay and dispersion during its passage from the point of measurement to the tar-get voxel. The dispersion is inherently coupled to the delay. Whereas the delay can easily assessed the bolus dispersion is caused by two proc-esses, the dispersion during its passage from the point of measurement to the tissue and the dispersion by the tissue passage expressed by the mean transit time.