Reiko Woodhams1,2, Mayumi Satou1, Hirofumi Hata1, Satoko Kakita1, Naoko Yoshimura3, Keiichi Iwabuchi4, Masanori Ozaki1, Shinichi Kan1
1Radiology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; 2Radiology, Brigham and Women's Hospital, Boston, MA, USA; 3Department of surgery, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan; 4Department of pathology, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan
This study evaluated optimal b-values for breast DWI.110 subjects (18 benign 92 malignant) were analyzed by comparing ADC values, signal to noise ratio (SNR) and tumor-normal contrast noise ratio (CNR) between b=1000 and 1500s/mm2in benignity and malignancy respectively. A b-value of1500s/mm2may be more appropriate for discrimination of histologic types because of increase of SNR and CNR with b-500s/mm2 from those with b-1000 s/mm2 in malignancy with smaller SNR and CNR. Inversely, b=1000s/mm2 will be more appropriate for screening purpose because of better SNR and CNR for benign as well as malignancy compared to those withb=1500s/mm2.