Meeting Banner
Abstract #4286

Comparison Between Internal and External Validation of in Vivo 31P MRS Quantification

Jon Dudley1, Wen-Jang Chu2,3, Xin Wang1, Matthew M. Norris1, Jing-Huei Lee1,3

1Biomedical Engineering, University of Cincinnati, Cincinnati, OH, USA; 2Psychiatry, University of Cincinnati, Cincinnati, OH, USA; 3Center for Imaging Research, University of Cincinnati, Cincinnati, OH, USA


Internal references are commonly used in in vivo MRS research. However, an internal reference for 31P MRS study may not be practical. This works is to investigate if an external reference can be reliable method for 31P MRS data by comparing its result with that obtained by an internal reference from 1H MRS data. The results showed that there is a strong correlation between these two approaches indicating that an external reference can be a reliable method.