Arnaud Guidon1, Allen W. Song1
1Brain Imaging and Analysis Center, Duke University, Durham, NC, USA
In this work, we present a new method aimed at achieving robust spectroscopic metabolite imaging in the presence of inhomogeneous magnetic fields. This technique is based on a new excitation strategy termed Bo anchor spatial excitation (BASE), which could take advantage of the recent advances in parallel transmission to achieve a region-specific, frequency-matched excitation. In particular, we show that BASE can help recover spectral resolution in regions where field heterogeneity would otherwise lead to severe off-resonance and dispersion effects. We anticipate that this method will find broad applications leading to more effective whole-brain spectroscopic imaging in vivo.