Hua Ai1, Brian A. Taylor1, Andrew M. Elliott1, Huong LePetross2, John D. Hazle1, Roger Jason Stafford1
1Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
A fast chemical shift imaging technique for real-time temperature imaging in the breast was investigated. The uncertainty in temperature was evaluated by measuring the proton resonant frequency shift between lipid and water at various points across the breast. Temperature uncertainty over 20s was about 3.0~3.6C. Calculated frequency difference is 13.8% percent lower than the expected quadrature sum of two frequencies, indicating that temperature uncertainty was consistently reduced by subtraction of lipid peak while the improvement was largely limited by low SNR. Moderate compression of breast is needed to minimize motion and hence temporal uncertainty in temperature.