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Abstract #4665

Depiction of SPIO in Atherosclerotic Plaque Using True Resolution SGM

Gopal Varma1, Marcus Richard Makowski1, Hannes Dahnke2, Stephen Keevil3, Rene M. Botnar1, Tobias Schaeffter1

1Division of Imaging Sciences, King's College London, London, UK; 2Philips Healthcare, Hamburg, Germany; 3Medical Physics, Guy's & St Thomas' NHS Foundation Trust, London, UK


Detection of atherosclerotic plaque with iron oxide contrast agents that induce a susceptibility effect in MRI is sometimes hindered by competing sources of negative contrast. Although positive contrast techniques aid in detection, hyper-intensities are often over-emphasised and may thus fail to accurately depict the plaque. We present a true resolution positive contrast method post-processing that provides a more accurate depiction of e.g. SPIO induced susceptibility effect with relation to its source.