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Abstract #4685

Effects of the Modulation in the White Matter Voxel Based Morphometry

Ozlem Ozmen Okur1, Cengizhan Ozturk1, Kubilay Aydin2

1Bogazici University Biomedical Engineering Institute, Istanbul, Turkey; 2Istanbul Medical School, Istanbul University, Instanbul, Turkey


Voxel Based Morphometry (VBM) aims to reveal the differences between different populations’ brains by making voxel based comparisons on MR brain images. SPM is quite a common tool utilized for VBM analyses. We computed the goodness of non-rigid registration metric (mutual information) in order to reveal the relationship between the registration quality and VBM results in SPM5 in case of with and without modulation. Additionally, we registered the images onto the groups’ own template (group averages), too; and evaluated these templates’ effects in the VBM analysis.