Jing Gu1, Yok-Lam Kwong2, Tao
Chan1, Wing-Yan Au2, Queenie Chan3, JingBo
Zhang1,4, Raymond Liang2, Pek-Lan Khong1
1Diagnostic Radiology, Queen Mary
Hospital, The University of Hong Kong, Hong Kong, China; 2Medicine,
Queen Mary Hospital, The University of Hong Kong, Hong Kong, China; 3Philips
Healthcare, Philips Electronics Hong Kong Limited, Hong Kong; 4Memorial
Sloan-Kettering Cancer Center, United States
The
aim of this study was to evaluate the diagnostic performance of DWIBS in
detection of lymphoma compared with PET/CT, and to assess the correlation
between ADC and SUV in lymphoma lesions. We found that (1) DWIBS provides
satisfactory diagnostic accuracy in lymphoma compared with PET/CT, and with
the advantage of no ionizing radiation. (2) There were significant
differences in ADCmin and SUVmax between aggressive and indolent B-cell
lymphoma. ADCmin may therefore be another useful quantitative marker for
tumor characterization and classification. (3) Negative correlation was found
between ADCmin and SUVmax suggesting an association between tumor cellularity
and metabolic activity.