Curtis Andrew Corum1,2, Djaudat Idiyatullin1,
Steen Moeller1, Ryan Chamberlain1, Deepali Sachdev2,3,
Michael Garwood1,2
1Center for Magnetic Resonance Research,
Dept. of Radiology, Medical School, University of Minnesota, Minneapolis, MN,
United States; 2Masonic Cancer Center, Medical School, University
of Minnesota, Minneapolis, MN, United States; 3Department of
Medicine, Medical School, University of Minnesota, Minneapolis, MN, United
States
Lung
and especially lung parenchyma are especially difficult to image with
MRI. T2* times are in the
sub-millisecond range and may require specialized hardware and methods to for
optimum visualization or quantitative information. Many lung pathologies such as inflamation
(asthma), primary and metastatic neoplasms (cancer) would benefit from more
robust and higher SNR methodologies.
SWIFT is a recently developed 3D radial imaging sequence, sensitive to
ultra-short T2 and T2* signals. We
demonstrate for the first time, free breathing prospectively gated 1H SWIFT
images of the mouse lung. Lung
parenchyma has significant signal and information content while bronchi
appear dark.