R Salomir1, M Viallon1, Joerg Roland2, Sylvain Terraz1, Denis Morel3, CD Becker1, P Gross2
1Radiologie, Hopital Universitaire de Genve, Geneva, Switzerland; 2Siemens Medical Solutions, Erlangen, Germany; 3Anesthesiology, University Hospitals of Geneva, Geneva, Switzerland
A new method for reference-less MR thermometry is described based on the fundamental theoretical frame of harmonic functions. The method was implemented for a thin open border and validated for 2D situation with HIFU heating in phantoms and in vivo rabbit thigh, and also with baseline acquisition in volunteers liver. Measurement accuracy in liver under free breathing was as good as 0.5C for 0.3 seconds temporal resolution. The method is insensitive to periodic or accidental motion, tissue expansion or drift, and to external perturbation from interventional device.