Stefan Zbyn1,2, Martin Krssak2, Mazda
Memarsadeghi2, Klaus Kubin2, Andrea Haitel3,
Michael Weber2, Thomas Helbich2, Ewald Moser1,
Siegfried Trattnig1,2, Stephan Gruber1,2
1MR Centre of Excellence, Medical
University of Vienna, Vienna, Austria; 2Department of Radiology,
Medical University of Vienna, Vienna, Austria; 3Department of
Pathology, Medical University of Vienna, Vienna, Austria
Since
spectral quality of prostate 3D-MRSI data vary dramatically within measured
volume, the total inaccuracies in (choline+creatine)/citrate (CC/C) ratios
using Cramr-Rao lower bounds were calculated to compare the accuracy of this
method between different prostate regions and measurement resolutions. Our
analysis suggests that voxels from prostate base and from periphery of the
prostate suffer the most from inaccurate CC/C ratios. To prevent from
misleading findings or time consuming manual inspection of spectral quality
in each prostate voxel, the metabolic-quality maps, that combine the
information of CC/C ratio and its accuracy in one image using the various
voxel transparencies, are demonstrated.