Sharon Giles1, Sophie F. Riches2, Veronica A. Morgan1, Catherine Simpkin1, Nandita deSouza2
1Cancer Research UK and EPSRC Cancer Imaging Centre, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; 2Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
We report T2, magnetisation transfer ratios, and apparent diffusion coefficients for prostate tissues at 3T. ADC showed a lower coefficient of variation for all prostate regions compared to other parameters, indicating it to be more reliable at differentiating tumor from non-tumor in the prostate. Negative correlation of ADC with MTR suggests that diffusion-weighted contrast may be linked to features other than cellularity, with presence of large macromolecules playing a role.