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Abstract #0580

Novel Spherical Phantoms for Q-Ball Imaging Under in Vivo Conditions

Amir Moussavi1, Bram Stieltjes2, Klaus H. Fritzsche3, Frederik B. Laun4

1Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany; 2Radiology, German Cancer Research Center, Heidelberg, Germany; 3Medical Imaging and Biological Informatics, German Cancer Research Center, Heidelberg, Germany; 4Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany


Spherical shaped diffusion phantoms that mimic in vivo fiber crossings are presented. Two crossing angles (45 and 90) and two packing types of the fibers in the crossing were realized (stacked and interleaved). The fractional anisotropy of individual fibers is can be adjusted between 0.52 and 0.95. High quality ODF maps with a voxel resolution of 2x2x5 mm were acquired using a standard diffusion weighted echoplanar diffusion sequence. Thus, the presented phantoms allow for validity measurements of Q-ball imaging and reconstruction approaches.