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Abstract #0636

Effect of Off-Frequency Encoding in Magnetic Resonance Elastography

Curtis L. Johnson1, Danchin Chen1, Harish Sharma2, Bradley P. Sutton, 2,3, William C. Olivero, 2,4, John G. Georgiadis1,2

1Mechanical Science and Engineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 2Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 3Bioengineering Department, University of Illinois at Urbana-Champaign, Urbana, IL, United States; 4Department of Neurosurgery, University of Illinois at Urbana-Champaign, Urbana, IL, United States


The effects of encoding displacement at a frequency other than the driving frequency with Magnetic Resonance Elastography (MRE) were investigated. Off-frequency responses can occur due to possible nonlinearities in the overall dynamic system being actuated. Results demonstrated that undesired off-frequency encoding could result in errors in mean estimated stiffness of tissue, as well as local fluctuations in estimated stiffness, which will have implications for MRE with nonlinear dynamic systems.