Matthew Mcgarry1, Irina Perreard2, Adam Jeffry Pattison1, Elijah van Houten3, John Weaver2, Keith Paulsen1
1Thayer School of Engineering, Dartmouth College, Hanover, NH, United States; 2Department of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States; 3Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand
This work demonstrates the improvements in in-vivo breast shear modulus reconstruction gained through considering the effects of viscoelasticity in a model-based, optimization driven MR elastography algorithm. Three cases with 12 reconstructions are presented where increased shear modulus in the region of a malignant tumor is apparent using a viscoelastic material model. It is shown that using an undamped linear elastic model produces inconclusive results. The improvements are due to a reduction in the model-data mismatch by using a viscoelastic model to fit tissue, which is known to have a significant viscous component.