Sahar Soleimanifard1, Khaled Z.
Abd-Elmoniem, 12, Harsh K. Agarwal1, Miguel
Santaularia-Tomas3, Tetsuo Sasano3, Evertjan Vonken3,
Amr Youssef3, M. Roselle Abraham3, Theodore P. Abraham3,
Jerry Ladd Prince1
1Department of Electrical and Computer
Engineering, Johns Hopkins University, Baltimore, MD, United States; 2National
Institute of Diabetes and Digestive and Kidney Diseases, National Institutes
of Health, Bethesda, MD, United States; 3Cardiology Division,
Department of Medicine, Johns Hopkins University, Baltimore, MD, United
States
Assessment
of tissue viability is currently involved with injection of gadolinium for
contrast-enhanced imaging. Strain profile of myocardium has been previously
studied but requires comparison of tensors fields, which is usually difficult
due to multivariate nature of tensors. It is desirable to describe tensors
with scalar indices, which are more mathematically and statistically
intuitive. In this work, fractional anisotropy (FA) of strain tensors in
healthy and infarcted regions in a large animal model is computed and
compared with conventional delayed-enhancement method. High correlation
between both representations shows promise of FA in assessment of viability
without negative effects of contrast agents.